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Author(s) -
Dübeler Anke,
Krastel Philipp,
Floss Heinz G.,
Zeeck Axel
Publication year - 2002
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/1099-0690(200203)2002:6<959::aid-ejoc959>3.0.co;2-a
Subject(s) - chemistry , shikimate pathway , stereochemistry , streptomyces , metabolite , acetal , lactone , cover (algebra) , organic chemistry , bacteria , biochemistry , biosynthesis , biology , genetics , enzyme , mechanical engineering , engineering
The cover picture shows the late biosynthetic steps of the antibiotic echinosporin (in the center of the picture) starting from chorismate. In the background one can see an agar plate of Streptomyces erythraeus (strain Tü 4015), the organism producing the tricyclic acetal‐lactone echinosporin. The mechanism shown, including a rearrangement and a Michael addition, represents a new branch of the shikimate pathway leading to a non‐aromatic metabolite. Details are discussed in the article by A. Zeeck et al. on page 983 ff.