Premium
Synthesis of Macrocyclic, Triazine‐Based Receptor Molecules
Author(s) -
Löwik Dennis W. P. M.,
Lowe Christopher R.
Publication year - 2001
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/1099-0690(200108)2001:15<2825::aid-ejoc2825>3.0.co;2-c
Subject(s) - chemistry , triazine , combinatorial chemistry , molecule , stereochemistry , organic chemistry
Abstract The synthesis of triazine‐based macrocyclic scaffolds is presented. The strategy employed allows for the facile functionalization of the macrocyclic molecules and combinatorial construction of putative receptor molecules. It is shown that the functional groups on the macrocyclic molecules, the size of the rings and the nature of the diamines linking the triazines can all be varied. In addition to the description of the stepwise synthesis of these compounds, it is shown that macrocycles based on triazine and xylenediamine are able to bind pyranosides and cyanuric acid.