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Conformational Analysis of meso ‐2,3,4,5‐Tetramethylhexane and Some of Its Derivatives
Author(s) -
Hoffmann Reinhard W.,
Menzel Karsten
Publication year - 2001
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/1099-0690(200107)2001:14<2749::aid-ejoc2749>3.0.co;2-t
Subject(s) - chemistry , stereocenter , octane , stereochemistry , substrate (aquarium) , enantioselective synthesis , organic chemistry , oceanography , geology , catalysis
Compounds 12 − 15 , meso ‐type 2,3,4,5,6,7‐hexasubstituted octane derivatives, have been synthesized using solely substrate‐based asymmetric induction. Thanks to the specific relative configurations at the six stereogenic centres, these compounds have a high tendency to populate the conformation with a fully extended zig‐zag backbone chain.