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Synthesis of New C 3h and C 3v Truxene Derivatives
Author(s) -
GómezLor Berta,
Frutos Óscar de,
Ceballos Plácido A.,
Granier Thierry,
Echavarren Antonio M.
Publication year - 2001
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/1099-0690(200106)2001:11<2107::aid-ejoc2107>3.0.co;2-f
Subject(s) - chemistry , isomerization , aryl , palladium , reagent , catalysis , tertiary alcohols , base (topology) , organic chemistry , combinatorial chemistry , alkyl , mathematical analysis , mathematics
Palladium‐catalyzed cross coupling of 2,7,12‐tribromotruxene with organostannanes and boronic acids leads to 2,7,12‐trisubstituted truxenes. 5,10,15‐Triarylated and trialkynylated truxene derivatives are obtained by the reaction of truxenone with aryl Grignard reagents or an alkynyllithium, followed by reduction of the tertiary alcohols with Et 3 SiH or BF 3 . syn ‐5,10,15‐Triarylated derivatives were obtained by the base‐catalyzed isomerization of the anti derivatives.