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Chiral, Polyionic Dendrimers with Complementary Charges − Synthesis and Chiroptical Properties
Author(s) -
Ritzén Andreas,
Frejd Torbjörn
Publication year - 2000
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/1099-0690(200011)2000:22<3771::aid-ejoc3771>3.0.co;2-1
Subject(s) - chemistry , dendrimer , enantioselective synthesis , chirality (physics) , combinatorial chemistry , computational chemistry , stereochemistry , nanotechnology , organic chemistry , catalysis , chiral symmetry , physics , materials science , quantum mechanics , nambu–jona lasinio model , quark
Chiral dendrimers up to the second generation have been prepared from enantiopure aromatic bis‐ and tris(amino acids) by peptide coupling techniques. The dendrimers could be deprotected to yield water‐soluble polyamine and/or polycarboxylic acid macromolecules. Two complementary types, with respect to the charges carried in water at pH = 7, were synthesised. A chiroptical study of the protected dendrimers, which were soluble in THF and CHCl 3 , was conducted. The results of that study indicate that the solution shapes of these dendrimers are rather decongested, with little steric interaction between different parts of the dendritic structure.