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Rakicidin C, A New Cyclic Depsipeptide from Streptomyces sp.
Author(s) -
Hu JinFeng,
Wunderlich Dirk,
Sattler Isabel,
Feng XiaoZhang,
Grabley Susanne,
Thiericke Ralf
Publication year - 2000
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/1099-0690(200010)2000:19<3353::aid-ejoc3353>3.0.co;2-e
Subject(s) - depsipeptide , chemistry , stereochemistry , cyclic peptide , glycine , glutamine , metabolite , strain (injury) , streptomyces , actinomycetales , amino acid , biochemistry , bacteria , peptide , biology , genetics , anatomy
Chemical screening of extracts of Actinomycetes strains has led to the detection, isolation, and structure elucidation of the new cyclic depsipeptide rakicidin C ( 1 ). The secondary metabolite from Streptomyces sp. (strain GT 61042) is built‐up from glutamine, N ‐methyl glycine, 4‐amino‐(2 E ,4)‐pentadienoic acid, and 3‐hydroxy‐2,4,6,8‐tetramethylnonanoic acid.