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Reactivity of Ph 2 P(O)py‐2 with Platinum(II) Alkyl Derivatives − Building‐up of a Chiral Phosphorus Atom through C,N‐Cyclometallation
Author(s) -
Minghetti Giovanni,
Doppiu Angelino,
Stoccoro Sergio,
Zucca Antonio,
Cinellu Maria Agostina,
Manassero Mario,
Sansoni Mirella
Publication year - 2002
Publication title -
european journal of inorganic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.667
H-Index - 136
eISSN - 1099-0682
pISSN - 1434-1948
DOI - 10.1002/1099-0682(20022)2002:2<431::aid-ejic431>3.0.co;2-k
Subject(s) - chemistry , reactivity (psychology) , substituent , medicinal chemistry , ligand (biochemistry) , platinum , cationic polymerization , stereochemistry , alkyl , crystal structure , crystallography , catalysis , polymer chemistry , organic chemistry , medicine , biochemistry , alternative medicine , receptor , pathology
The reaction of Ph 2 P(O)py‐2 (HL) with methyl‐ and dimethylplatinum(II) derivatives afforded a series of six‐membered C , N ‐cyclometallated species, [PtX(L′)(L)] (X=halide or Me; L′ = neutral ligand, e.g. SMe 2 , SOMe 2 , CO, PAr 3 ) arising from activation of one C(sp 2 )−H bond of a phenyl substituent. The metallation entailed elimination of methane and caused the phosphorus atom to become chiral. The series includes the complex [Pt(Me)(CO)(L)] where the platinum atom is bonded to three different carbon atoms (C sp 3, C sp 2, C sp ). From the neutral species cationic derivatives [Pt(L′)(L′′)(L)] + (L′ = SMe 2 , L′′ = CH 3 CN; L′−L′′ = dppe; L′ = SMe 2 or SOMe 2 , L′′ = H 2 O) could be obtained. The new complexes were isolated and fully characterised by elemental analyses and spectroscopic techniques (IR, NMR, FAB‐MS). The solid‐state structures of [PtCl(SMe 2 )(L)], [PtCl(CO)(L)], [Pt(Me)(SOMe 2 )(L)], and [Pt(SMe 2 )(H 2 O)(L)][BF 4 ] were determined by single‐crystal X‐ray diffraction.