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1,2‐Additions of Organomagnesium Halides to Phosphaalkynes: Synthesis of 2‐Phospha‐1‐vinylmagnesium Halides and a Novel Type of Magnesium‐Phosphorus Cage Compound
Author(s) -
Renner Jens,
Bergsträßer Uwe,
Binger Paul,
Regitz Manfred
Publication year - 2000
Publication title -
european journal of inorganic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.667
H-Index - 136
eISSN - 1099-0682
pISSN - 1434-1948
DOI - 10.1002/1099-0682(200011)2000:11<2337::aid-ejic2337>3.0.co;2-4
Subject(s) - chemistry , halide , isopropyl , magnesium , medicinal chemistry , phosphorus , reagent , stereoselectivity , chloride , organic chemistry , inorganic chemistry , catalysis
Grignard reagents such as isopropyl‐ and tert ‐butylmagnesium halide ( 2a: X = Cl ; 2b: X = Br) react with tert ‐butylphosphaacetylene (1) in a regio‐ and stereoselective 1,2‐addition process at −78 °C to give the 2‐phospha‐1‐vinylmagnesium halides 3a,b in high yields. At elevated temperatures, the phosphavinylmagnesium chloride 3a reacts with two more equivalents of 1 to afford the previously unknown magnesium‐phosphorus cage compound 4 , the structure of which has been confirmed by X‐ray‐analysis.