Premium
Exposure to ozone inhibits isolation‐induced aggressive behavior of adult CD‐1 male mice
Author(s) -
Petruzzi S.,
Fiore M.,
Dell'Omo G.,
Alleva E.
Publication year - 1995
Publication title -
aggressive behavior
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.223
H-Index - 92
eISSN - 1098-2337
pISSN - 0096-140X
DOI - 10.1002/1098-2337(1995)21:5<387::aid-ab2480210508>3.0.co;2-0
Subject(s) - aggression , ozone , physiology , toxicology , psychology , chemistry , medicine , biology , developmental psychology , organic chemistry
Continuous exposure to ozone (O 3 , 1.2 ppm) in adult CD‐1 male mice for 20 consecutive days markedly influenced a number of items of aggressive behavior induced by 59 days of individual housing. The behavior of mice was videotaped on days 1, 3, and 5 of five consecutive daily encounters (10 min each; isolation days 55, 57, and 59). Ozone exposure caused an abatement of aggressive behavior and enhanced fear‐associated displays shown by a significant decrease in the frequency of attacking and digging and an increase in freezing. Moreover, O 3 induced a decrease of time spent in attacking and exploration/activity. Nonexposed animals exhibited a day‐dependent increase in self‐grooming frequency which was not observed in O 3 mice; by contrast, freezing was higher in O 3 mice on day 5 of the test. Data suggest that O 3 exposure produces a remarkable reduction of mouse aggression, indirectly confirming previous findings on physical and neurobehavioral effects of O 3 . © 1995 Wiley‐Liss, Inc.