Premium
New antiarrhythmic agents: a conceptually novel approach
Author(s) -
Mátyus Péter,
Rettegi Tivadar,
Varró András,
Papp Julius Gy.
Publication year - 2000
Publication title -
medicinal research reviews
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.868
H-Index - 130
eISSN - 1098-1128
pISSN - 0198-6325
DOI - 10.1002/1098-1128(200007)20:4<294::aid-med2>3.0.co;2-5
Subject(s) - antiarrhythmic agent , electrophysiology , pharmacology , chemistry , anti arrhythmia agents , medicine , cardiology , heart disease , atrial fibrillation
Synthesis and biological evaluation of novel phenoxyalkyl amines exhibiting both class Ib and class III type electrophysiological properties are described. Two compounds showed excellent antiarrhythmic effects against reperfusion induced arrhythmias. © 2000 John Wiley & Sons, Inc. Med Res Rev, 20, No. 4, 294–303, 2000