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Is sham feeding an animal model of bulimia?
Author(s) -
van Vort Walter B.
Publication year - 1988
Publication title -
international journal of eating disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.785
H-Index - 138
eISSN - 1098-108X
pISSN - 0276-3478
DOI - 10.1002/1098-108x(198811)7:6<797::aid-eat2260070610>3.0.co;2-k
Subject(s) - binge eating , feeding behavior , sham feeding , psychology , taste , taste aversion , neuroscience , developmental psychology , endocrinology , biology , clinical psychology , eating disorders , stimulation
Studies of sham‐feeding animals are useful in dissociating the hedonic, orosensory effects of food in the mouth from the satiating and nutritive effects of food in the gut, an operational state highly analogous to binge eating with vomiting. Alteration of hedonic and postingestive responses to food may occur physiologically or may be conditioned; binge‐like behavior can result when regulatory processes are sufficiently distorted by biological or environmental changes. An important role for satiety‐inducing neuropeptides and central dopamine activity during binging is inferred from the model.