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Multiblock copolymers based on segments of poly ( D,L ‐lactic‐glycolic acid) and poly(ethylene glycol) or poly(ϵ‐caprolactone): A comparison of their thermal properties and degradation behavior
Author(s) -
Penco Maurizio,
Bignotti Fabio,
Sartore Luciana,
D'Antone Salvatore,
D'Amore Alberto
Publication year - 2000
Publication title -
journal of applied polymer science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.575
H-Index - 166
eISSN - 1097-4628
pISSN - 0021-8995
DOI - 10.1002/1097-4628(20001205)78:10<1721::aid-app20>3.0.co;2-6
Subject(s) - glycolic acid , differential scanning calorimetry , ethylene glycol , materials science , thermogravimetric analysis , polymer chemistry , caprolactone , copolymer , thermal stability , glass transition , crystallinity , polyester , peg ratio , diol , chemical engineering , lactic acid , polymer , composite material , genetics , physics , finance , bacteria , economics , engineering , biology , thermodynamics
A comparison of the thermal properties of two classes of poly( D,L ‐lactic‐glycolic acid) multiblock copolymers is reported. In particular, the results of differential scanning calorimetry, and thermogravimetric analysis of copolymers containing poly(ethylene glycol) (PEG) or diol‐terminated poly(ϵ‐caprolactone) (PCDT) segments are described. The influence of the chemical structure and the length of PEG and PCDT on thermal stability, degree of crystallinity and glass transition temperature ( T g ) is discussed. Finally, an evaluation of the hydrolytic behavior in conditions mimicking the physiological environment is reported. © 2000 John Wiley & Sons, Inc. J Appl Polym Sci 78: 1721–1728, 2000