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Allgrove syndrome in adulthood
Author(s) -
Bentes Carla,
SantosBento Mariana,
de Sá Joāo,
de Lurdes Sales Luís Maria,
de Carvalho Mamede
Publication year - 2001
Publication title -
muscle and nerve
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 145
eISSN - 1097-4598
pISSN - 0148-639X
DOI - 10.1002/1097-4598(200102)24:2<292::aid-mus160>3.0.co;2-x
Subject(s) - medicine , dysphagia , dysarthria , tetraparesis , achalasia , polyneuropathy , drooling , adrenal insufficiency , atrophy , surgery , audiology , pathology , radiology , magnetic resonance imaging , esophagus
A 35‐year‐old man with a past history of achalasia developed progressive spastic tetraparesis, distal limb atrophy, dysarthria, and dysphagia. A clinical diagnosis of amyotrophic lateral sclerosis (ALS) was considered before neurophysiological investigation, which disclosed a polyneuropathy and a prolonged central conduction time. One year later, the patient developed dysautonomic symptoms. Following confirmation of adrenal insufficiency, a diagnosis of Allgrove syndrome was made. This is a rare case, and we emphasize its clinical similarity with ALS. © 2001 John Wiley & Sons, Inc. Muscle Nerve 24: 292–296, 2001