Premium
Motor cortex disinhibition of the unaffected hemisphere after acute stroke
Author(s) -
Liepert Joachim,
Hamzei Farsin,
Weiller Cornelius
Publication year - 2000
Publication title -
muscle and nerve
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 145
eISSN - 1097-4598
pISSN - 0148-639X
DOI - 10.1002/1097-4598(200011)23:11<1761::aid-mus14>3.0.co;2-m
Subject(s) - disinhibition , transcranial magnetic stimulation , stroke (engine) , hemiparesis , motor cortex , facilitation , neuroscience , medicine , physical medicine and rehabilitation , psychology , stimulation , mechanical engineering , engineering , angiography
Abstract We studied motor cortex excitability in the nonlesioned hemisphere of patients with a large cortical infarction. Patients with a severe hemiparesis due to a stroke were compared with age‐matched, healthy controls. Paired transcranial magnetic stimuli were applied over the unaffected hemisphere to investigate intracortical inhibition and facilitation. In the patient group, intracortical inhibition was reduced. We suggest that this disinhibition is due to an impairment of transcallosal fibers and may affect recovery. © 2000 John Wiley & Sons, Inc. Muscle Nerve 23: 1761–1763, 2000.