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Reproducibility of intracortical inhibition and facilitation using the paired‐pulse paradigm
Author(s) -
Boroojerdi Babak,
Kopylev Leonid,
Battaglia Fortunato,
Facchini Stefano,
Ziemann Ulf,
Muellbacher Wolf,
Cohen Leonardo G.
Publication year - 2000
Publication title -
muscle and nerve
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 145
eISSN - 1097-4598
pISSN - 0148-639X
DOI - 10.1002/1097-4598(200010)23:10<1594::aid-mus19>3.0.co;2-3
Subject(s) - reproducibility , transcranial magnetic stimulation , facilitation , coefficient of variation , silent period , pulse (music) , psychology , physical medicine and rehabilitation , neuroscience , medicine , stimulation , statistics , mathematics , computer science , telecommunications , detector
We have evaluated the reproducibility of intracortical inhibition (ICI) and facilitation (ICF) studied with paired‐pulse focal transcranial magnetic stimulation. Three investigators studied the same subjects ( n = 4) in three different sessions. A high variability was shown across subjects [coefficient of variation, (cv) 67.3% for ICI and 21.2% for ICF]. Intersession variability was up to 37.1% for ICI and 22.7% for ICF. Interinvestigator variability was 17.3% for ICI and negligible for ICF. Our results may have implications for planning future studies. © 2000 John Wiley & Sons, Inc. Muscle Nerve 23: 1594–1597, 2000