Premium
Limits of the sympathetic skin response in patients with diabetic polyneuropathy
Author(s) -
Bril Vera,
Nyunt Muya,
Ngo Mylan
Publication year - 2000
Publication title -
muscle and nerve
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 145
eISSN - 1097-4598
pISSN - 0148-639X
DOI - 10.1002/1097-4598(200009)23:9<1427::aid-mus15>3.0.co;2-p
Subject(s) - medicine , polyneuropathy , sural nerve , autonomic neuropathy , diabetes mellitus , peripheral neuropathy , peripheral , autonomic nervous system , diabetic neuropathy , cardiology , anesthesia , surgery , endocrinology , heart rate , blood pressure , biology , genetics , cell culture , neuroblastoma
We performed upper‐ and lower‐limb sympathetic skin responses (SSRs) in a series of 337 diabetic patients with and without peripheral polyneuropathy and 38 reference subjects. We did not find any correlations between SSRs and symptoms of pain or autonomic dysfunction. The SSR correlated more strongly with vibration perception threshold (VPT) and sural nerve amplitude than with cooling detection threshold (CDT) or clinical symptoms. We conclude that current limitations inherent in SSR testing preclude its use as a reliable and consistent index of the autonomic dysfunction commonly encountered in diabetic patients. © 2000 John Wiley & Sons, Inc. Muscle Nerve 23: 1427–1430, 2000