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1 H NMRD profiles of diamagnetic proteins: a model‐free analysis †
Author(s) -
Bertini Ivano,
Fragai Marco,
Luchinat Claudio,
Parigi Giacomo
Publication year - 2000
Publication title -
magnetic resonance in chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.483
H-Index - 72
eISSN - 1097-458X
pISSN - 0749-1581
DOI - 10.1002/1097-458x(200007)38:7<543::aid-mrc722>3.0.co;2-#
Subject(s) - chemistry , diamagnetism , chemical physics , crystallography , nuclear magnetic resonance , magnetic field , physics , quantum mechanics
Abstract A model‐free analysis of the 1 H nuclear magnetic relaxation dispersion (NMRD) profiles of 14 proteins in aqueous solution was performed to reproduce the experimental dispersions, that are stretched with respect to Lorentzians. The analysis, according to a recently proposed approach, shows a good correlation of all physically meaningful parameters with the molecular weight of the proteins, spanning the range from 6500 to 480000, and, in particular, of the average correlation time with the Stokes–Einstein estimate of the rotational correlation time. Copyright © 2000 John Wiley & Sons, Ltd.