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Treatment of giant cell granuloma of the maxilla with intralesional injection of steroids
Author(s) -
Khafif Avi,
Krempl Greg,
Medina Jesus E.
Publication year - 2000
Publication title -
head and neck
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.012
H-Index - 127
eISSN - 1097-0347
pISSN - 1043-3074
DOI - 10.1002/1097-0347(200012)22:8<822::aid-hed12>3.0.co;2-w
Subject(s) - medicine , maxilla , granuloma , giant cell , lesion , mandible (arthropod mouthpart) , head and neck , central giant cell granuloma , surgery , pathology , anatomy , biology , botany , genus
Background Giant cell granuloma is rare in the head and neck region and most commonly affects the maxilla and mandible. Although it is a benign disease process, it may be locally destructive. Surgery is the treatment currently recommended. Because of the location of the disease, surgery may be disfiguring. Because it is a benign process, less radical nonsurgical treatment alternatives are desirable. Methods A case report of a giant cell granuloma treated with steroid injections. Results After six weekly intralesional steroid injections, a giant cell granuloma of the maxilla became calcified and smaller. After a follow‐up period of 2 years, there was no evidence of regrowth, and the bony osteolytic lesion had filled with bone. A review of the literature revealed two case reports of successful steroid injections with similar response. Conclusions Steroid injections are a viable alternative in the treatment of giant cell granuloma, which may avoid surgery. © 2000 John Wiley & Sons, Inc. Head Neck 22: 822–825, 2000.