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Fine‐needle aspiration findings in nodular myositis: A case report
Author(s) -
Layfield Lester J.,
Crim Julia,
Gupta Dilip
Publication year - 2000
Publication title -
diagnostic cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 65
eISSN - 1097-0339
pISSN - 8755-1039
DOI - 10.1002/1097-0339(200011)23:5<343::aid-dc12>3.0.co;2-k
Subject(s) - medicine , soft tissue , pathology , polymyositis , myositis , fine needle aspiration , lesion , biopsy
Fine‐needle aspiration (FNA) is frequently the initial diagnostic modality for the workup of suspected metastatic disease in subcutaneous or deeper soft tissues. The technique is less well‐accepted for the diagnosis of primary soft‐tissue lesions. Occasionally during the investigation of suspected metastatic disease, primary processes of the soft tissues will undergo FNA. Thus, familiarity with the cytomorphology of soft‐tissue reparative and neoplastic lesions is important. A variety of reparative and degenerative entities exist within the soft tissues, one of which is localized nodular myositis. This lesion may be a precursor of generalized polymyositis, including polymyositis associated with graft vs. host disease, or it may remain a localized process. Aspirates from localized nodular myositis demonstrate fragments of striated muscle including degenerating and regenerative myocytes, a mixed inflammatory background, and necrotic debris. Cytologic identification of this lesion can be therapeutically important, particularly in post‐bone marrow transplant patients. Diagn. Cytopathol. 2000;23:343–347. © 2000 Wiley‐Liss, Inc.