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Fine‐needle aspiration cytology of Schiller‐Duval bodies of yolk‐sac tumor
Author(s) -
Yang Grace C.H.
Publication year - 2000
Publication title -
diagnostic cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 65
eISSN - 1097-0339
pISSN - 8755-1039
DOI - 10.1002/1097-0339(200010)23:4<228::aid-dc2>3.0.co;2-m
Subject(s) - medicine , yolk sac , cytology , pathology , cytopathology , fine needle aspiration cytology , fine needle aspiration , anatomy , biopsy , embryo , microbiology and biotechnology , biology
The objective of this study was to find the cytological equivalent of Schiller‐Duval bodies seen in histology in order to employ the findings as a diagnostic clue for yolk‐sac tumor (YST) in aspiration biopsy. A YST, aspirated from the retroperitoneal lymph node of a 29‐yr‐old Asian man with testicular complex mature teratoma, contained numerous Schiller‐Duval bodies on cell block sections. In the corresponding smears, a network of tumor cell‐coated, anastomosing, thin‐walled, rigid hematopoietic channels with dramatic changes in diameter was observed, in agreement with the diagram based on the reconstruction of 48 serial plastic sections done by Kazancigil et al. (Am J Cancer 1940;40:199–212). In addition, some of the hematopoietic channels folded over several times like a long, narrow balloon pinched at its joints, i.e., “balloon animal”‐like. Many segments of the allantoic viteline vascular network, fractured by smearing, exhibited three‐ or four‐way branchings, bulbous protrusions, and cauliflower‐like branchings of widely variable diameter. Diagn. Cytopathol. 2000;23:228–232. © 2000 Wiley‐Liss, Inc.