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Aspiration and imprint cytopathology of thyroid carcinoma associated with familial adenomatous polyposis
Author(s) -
Chong JaMun,
Koshiishi Naoki,
Kurihara Katsumi,
Kubono Sachiko,
Kawai Toshiro,
Fukayama Masashi
Publication year - 2000
Publication title -
diagnostic cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 65
eISSN - 1097-0339
pISSN - 8755-1039
DOI - 10.1002/1097-0339(200008)23:2<101::aid-dc7>3.0.co;2-0
Subject(s) - medicine , familial adenomatous polyposis , cytopathology , thyroid carcinoma , thyroid , pathology , fine needle aspiration , carcinoma , biopsy , papillary carcinoma , thyroid cancer , aspiration biopsy , cancer , colorectal cancer , cytology
Thyroid carcinomas occur in association with familial adenomatous polyposis (FAP), and some are the first symptom of FAP. Although several histological features have been reported, the cytopathology of FAP‐associated thyroid carcinoma has not yet been described. We report on two cases of FAP‐associated thyroid carcinomas diagnosed by fine‐needle aspiration biopsy and one case imprinted after resection. All 3 patients belonged to the same family, and thyroid carcinoma was the first symptom of the proband. Cytological features include fascicular or whorl formation of spindle cells with papillary, follicular, and/or solid architectures, in addition to the typical features of papillary carcinoma. The cytological features of FAP‐associated thyroid carcinomas are characteristic and may suggest FAP. Diagn. Cytopathol. 23:101–105, 2000. © 2000 Wiley‐Liss, Inc.