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Infrared spectroscopy of human cells and tissue. VIII. Strategies for analysis of infrared tissue mapping data and applications to liver tissue
Author(s) -
Diem Max,
Chiriboga Luis,
Yee Herman
Publication year - 2000
Publication title -
biopolymers
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.556
H-Index - 125
eISSN - 1097-0282
pISSN - 0006-3525
DOI - 10.1002/1097-0282(2000)57:5<282::aid-bip50>3.0.co;2-r
Subject(s) - infrared , liver tissue , infrared spectroscopy , chemistry , spectroscopy , pathology , nuclear magnetic resonance , optics , physics , medicine , organic chemistry , quantum mechanics
Experimental and computational methods of infrared microspectroscopy (IRI‐MSP) and infrared spectral mapping (ISM) are presented. These methods are subsequently applied to the analysis of cirrhotic liver tissue. The sensitivity of infrared spectral mapping toward spectral changes caused by disease will be demonstrated. In addition, the excellent agreement between ISM data and histopathological information will be discussed. © 2000 John Wiley & Sons, Inc. Biopolymers (Biospectroscopy) 57: 282–290, 2000