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Preservation of visual fields after peri‐sellar gamma‐knife radiosurgery
Author(s) -
Ove Roger,
Kelman Shalom,
Amin Pradip P.,
Chin Lawrence S.
Publication year - 2000
Publication title -
international journal of cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.475
H-Index - 234
eISSN - 1097-0215
pISSN - 0020-7136
DOI - 10.1002/1097-0215(20001220)90:6<343::aid-ijc6>3.0.co;2-h
Subject(s) - optic chiasm , radiosurgery , medicine , pituitary adenoma , visual field , radiation therapy , optic nerve , optic neuropathy , meningioma , radiology , optic chiasma , surgery , nuclear medicine , adenoma , ophthalmology , pathology
Radiosurgical treatment of pituitary and peri‐sellar tumors has become an increasingly utilized modality as an alternative to conventional radiotherapy and surgery. Such radiosurgery results in a relatively high dose of radiation to the optic chiasm. The clinical data establishing safe single‐fraction doses to the chiasm is immature, although taken together previous literature suggests a recommended maximal dose of 8 Gy. Optic neuropathy, when it occurs, tends to take place within 2 years of treatment. We evaluated the visual fields of 20 sequential patients that received significant doses to the optic chiasm by Gamma‐knife radiosurgery. There were 17 cases of pituitary adenoma and 3 cases of meningioma, and two patients refused follow‐up testing. Preoperative visual field and cranial nerve examinations were done prior to radiosurgery and in follow‐up, with a median follow‐up of 24 months. There were no cases of quantitative visual field deficit induced by treatment. No patients developed symptomatic visual deterioration. Radiat. Oncol. Invest. 90:343–350, 2000. 2000 Wiley‐Liss, Inc.