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Lymphoma and lymphoid leukemia incidence in Florida children
Author(s) -
Wilkinson James D.,
Fleming Lora E.,
MacKin Jill,
Voti Lydia,
WohlerTorres Bradley,
Peace Steven,
Trapido Edward
Publication year - 2001
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(20010401)91:7<1402::aid-cncr1145>3.0.co;2-6
Subject(s) - medicine , lymphoma , leukemia , incidence (geometry) , cancer , confidence interval , hodgkin lymphoma , lymphoid leukemia , oncology , optics , physics
BACKGROUND Incidence reports for pediatric lymphoma and lymphoid leukemia in Hispanic subpopulations in the United States are rare. The authors hypothesized that Florida's Hispanic children would have higher risks of lymphoma and lymphoid leukemia compared with non‐Hispanic white children. METHODS All cases of lymphoid leukemia, Hodgkin, non‐Hodgkin, and Burkitt lymphoma (SEER International Classification of Diseases for Oncology codes) in children (< 15 years) in the Florida Cancer Data System (FCDS) from 1985 to 1997 were studied. Cases were classified as: 1) white, 2) Hispanic, or 3) black, and stratified by age. Age‐adjusted rates for the three race‐ethnic groups were calculated. Rates for Hispanics and blacks were compared with whites as standardized rate ratios (SRR) with 95% confidence intervals. RESULTS Seven hundred thirty‐one incident cases of pediatric lymphoma and 1231 cases of lymphoid leukemia were identified during the study period. For children with lymphoma, the SRR for Hispanics was 1.32 (95% CI, 1.20–1.44), and for blacks, the SRR was 0.68 (95% CI, 0.63–0.72. For lymphoid leukemia, the SRR for Hispanics was 1.29 (95% CI, 1.28–1.30), and for blacks, the SRR was 0.55 (95% CI, 0.54–0.56). Similar rates were found for the Hodgkin and non‐Hodgkin subgroups. CONCLUSIONS Incidences of Hodgkin and non‐Hodgkin lymphoma were significantly higher in Florida's Hispanic children, with 30% increased relative risks, compared with whites. Black children had significantly decreased incidences and risk. Results for lymphoid leukemia were similar. Incidence of lymphoma in Florida's Hispanic children (primarily Cuban and Central American origin) differed from similar reports from Texas and California, where Hispanics are primarily of Mexican origin. Cancer 2001;91:1402–8. © 2001 American Cancer Society.