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Could chest X‐ray screening for lung cancer be cost‐effective?
Author(s) -
Caro J. Jaime,
Klittich Wendy S.,
Strauss Gary
Publication year - 2000
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(20001201)89:11+<2502::aid-cncr32>3.0.co;2-n
Subject(s) - medicine , lung cancer , cost effectiveness , cancer , years of potential life lost , quality adjusted life year , lung cancer screening , population , demography , environmental health , oncology , life expectancy , risk analysis (engineering) , sociology
BACKGROUND Currently, no screening program for lung cancer is advocated, yet recent review of the clinical trials has raised questions about the conclusion that it would not be effective. If a screening program is to be considered, its potential economic impact needs to be assessed. METHODS An economic model was created comparing lung cancer mortality in male smokers ages 45–80 years, screened versus unscreened. Estimates of the potential reduction in mortality and cost of screening are applied. The outcomes of the model include deaths avoided, life years gained, net costs, and cost‐effectiveness. RESULTS The base analysis (mortality reduction of 18%) estimates that nearly 3000 deaths would be avoided in a population of 100,000 male smokers age 40–80 years, at a cost‐effectiveness of $9000 per undiscounted life year gained. A program resulting in only 6% mortality reduction would increase the ratio to $25,000 per undiscounted life years gained. CONCLUSIONS If further examination of lung cancer screening supports its effectiveness, the results of this model suggest that implementation would be economically efficient. Cancer 2000;89:2502–5. © 2000 American Cancer Society.