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The Mayo Lung Project
Author(s) -
Fontana Robert S.
Publication year - 2000
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(20001201)89:11+<2352::aid-cncr7>3.0.co;2-5
Subject(s) - medicine , lung , general surgery , intensive care medicine
BACKGROUND The Mayo Lung Project (MLP) was a randomized, controlled, clinical trial designed to determine whether intensive radiologic and cytologic screening for lung carcinoma could reduce lung carcinoma mortality significantly. METHODS Half the MLP population was encouraged (and reminded) to undergo free chest X‐rays and free sputum cytology tests every 4 months for 6 years, whereas the other half of the population was advised to undergo the 2 tests yearly. RESULTS Lung carcinoma incidence rate, resectability, and survivorship were greater in the intensively screened group compared with the control group, but there was no significant difference in the lung carcinoma mortality rate between the two groups. CONCLUSIONS The intensive screening program cannot be recommended as a public health measure because it did not appear to result in decreased lung carcinoma mortality, even though it did yield an increased rate of incidence of apparently indolent tumors. Cancer 2000;89:2352–5. © 2000 American Cancer Society.