Premium
Prognostic factors in head and neck soft tissue sarcomas
Author(s) -
Dudhat Sanjay B.,
Mistry Rajesh C.,
Varughese Thomas,
Fakih Abdul R.,
Chinoy Roshan F.
Publication year - 2000
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(20000815)89:4<868::aid-cncr20>3.0.co;2-9
Subject(s) - medicine , soft tissue , head and neck , univariate analysis , medical record , retrospective cohort study , survival rate , prognostic variable , multivariate analysis , surgery , overall survival , radiology , oncology
BACKGROUND Soft tissue sarcomas of head and neck constitute a heterogeneous group of rare malignant tumors occurring at rare sites. The purpose of this retrospective study is to evaluate the pathologic features, treatment modalities, outcome, patterns of failure, survival, and other prognostic factors. METHODS The medical records of 72 patients whose tumors were diagnosed as head and neck sarcomas, treated at Tata Memorial Center between 1981 to 1995 were reviewed. Potential prognostic factors including age, gender, tumor size, histology, grade, and adjuvant treatment were evaluated. RESULTS The overall and disease free survival at 5 years was 60% and 45%, respectively. The median survival and follow‐up was 76 and 38 months, respectively. Thirty‐two patients (44.4%) developed recurrence of which 13 patients were salvaged. The univariate and multivariate analysis showed tumor size and grade as important prognostic factors for the survival. CONCLUSIONS Tumor size greater than 5 cm and high grade tumors were important prognostic factors for survival. Every effort should be made for early diagnosis and wide surgical excision. For localized recurrent tumors without evidence of distant metastasis, surgery should be attempted whenever possible. High rates of locoregional failure in head and neck area indicate the need for improved treatment strategies. Cancer 2000;89:868–72. © 2000 American Cancer Society.