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Image‐guided core‐needle biopsy in patients with suspected or recurrent lymphomas
Author(s) -
de Kerviler Eric,
Guermazi Ali,
Zagdanski AnneMarie,
Meignin Véronique,
Gossot Dominique,
Oksenhendler Eric,
Mariette Xavier,
Brice Pauline,
Frija Jacques
Publication year - 2000
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(20000801)89:3<647::aid-cncr21>3.0.co;2-r
Subject(s) - medicine , lymphoma , biopsy , radiology , surgery
BACKGROUND It is now commonly admitted that the diagnosis of recurrence of lymphoma can be assessed by image‐guided needle biopsy (IGNB). However, the means of obtaining tissue for the original diagnosis of lymphoma is often surgery. The aim of this study was to compare the accuracy of IGNB at the time of diagnosis and at the time of recurrence or progression. METHODS The authors performed 212 IGNBs on 194 patients who eventually had a diagnosis of lymphoma. One hundred three IGNBs were obtained at original diagnosis and 109 at recurrence or progression. Large‐cutting core‐biopsy needles, ranging in size from 20 gauge to 14 gauge, were used. Immunohistochemistry studies were performed in all lymphoma cases. RESULTS A diagnosis of lymphoma with subtyping was obtained in 88% of all cases, in 85% at initial diagnosis, and in 89% at follow‐up. Therapy was initiated on the basis of IGNB in 93% of all cases, in 91% at initial diagnosis, and in 94% at follow‐up. Benign complications occurred in 7.5% of cases and did not require specific treatment. IGNB was equally effective for making a specific diagnosis of lymphoma and initiating therapy at the time of original diagnosis and at follow‐up. CONCLUSIONS The authors recommend that IGNB be performed as the initial procedure for the diagnosis of lymphoma in the absence of peripheral lymph nodes, either at presentation or at recurrence. Cancer 2000;89:647–52. © 2000 American Cancer Society.