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Carcinoid of the ampulla of vater. Clinical characteristics and morphologic features
Author(s) -
Hatzitheoklitos Efthimios,
Büchler Markus W.,
Friess Helmut,
Poch Bertram,
Ebert Matthias,
Mohr Winfried,
Imaizumi Toshihide,
Beger Hans G.
Publication year - 1994
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19940315)73:6<1580::aid-cncr2820730608>3.0.co;2-0
Subject(s) - medicine , ampulla of vater , ampulla , general surgery , pathology , anatomy , carcinoma
Background. Carcinoid tumors of the gastrointestinal tract are most common localized in the appendix, followed by the small intestine, the rectum, and the stomach. The localization of these tumors at the ampulla of Vater is extremely seldom. Methods. In the present study the authors describe two patients with carcinoid tumors of the ampulla Vater and review 71 previously published cases. Results. Most patients presented with jaundice, but without carcinoid syndrome. Because the tumor grows submucosally, preoperative diagnosis was correct only in 15%. Most tumors were around 2 cm in size. Metastasis to lymph nodes and/or liver was present in 45%. Standard treatment is Whipple resection or local excision in small tumors. Conclusions. Carcinoid tumors of the ampulla of Vater are an extremely rare clinical entity. Generally, the prognosis is good with a 5‐year survival period of 90%.