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Malignant lymphoma of bladder. Report of three cases and review of the literature
Author(s) -
Ohsawa Masahiko,
Aozasa Katsuyuki,
Horiuchi Keisuke,
Kanamaru Akihisa
Publication year - 1993
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19930915)72:6<1969::aid-cncr2820720630>3.0.co;2-a
Subject(s) - medicine , lymphoma , malignant lymphoma , urinary bladder , follicular lymphoma , urinary system , nodule (geology) , pathology , lesion , gross hematuria , surgery , paleontology , biology
Background . The significance of long‐standing cystitis has been postulated as a causal factor in malignant lymphoma of bladder. Methods . The authors reviewed 3 cases of primary malignant lymphoma of the urinary bladder and an additional 27 cases described in the literature (25 from Western countries and 2 from Japan). Clinical and pathologic findings in the total 30 cases are summarized. Results . The majority of patients presented with gross hematuria and were between 20 and 85 years of age (median age, 64 years). Marked female preponderance was found (male to female ratio, 1:6.5). Six patients (20%), all of whom were women, out of 30 had a history of chronic cystitis. Macroscopic findings showed a solitary mass (22 cases), multiple masses (6 cases), or a diffuse lesion without nodule formation (2 cases). The vast majority of bladder lymphoma were non‐Hodgkin lymphoma (NHL) of B‐cell type; among them, 14% were follicular lymphomas. Follow‐up indicated that NHL of bladder had a favorable prognosis. Conclusions . Malignant lymphoma of bladder is characterized by a preponderance in women, who are occasionally affected by chronic cystitis.