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Influence of socioeconomic status on prognosis of colorectal cancer. A population‐based study in Cǒte D'Or, France
Author(s) -
Monnet E.,
Boutron M. C.,
Faivre J.,
Milan C.
Publication year - 1993
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19930815)72:4<1165::aid-cncr2820720406>3.0.co;2-5
Subject(s) - medicine , socioeconomic status , colorectal cancer , residence , population , cancer , social class , stage (stratigraphy) , confidence interval , proportional hazards model , palliative care , demography , performance status , gerontology , environmental health , paleontology , nursing , sociology , political science , law , biology
Background . The prognostic significance of the socioeconomic status of patients treated for colorectal cancer, although stated in some studies, remains controversial. Methods . The authors studied a population‐based series of 771 patients with colorectal cancer diagnosed in Čote D'Or, France, between January 1976 and December 1980. Survival was studied for the first 5 years after diagnosis. The relationship between socioeconomic status, assessed by comfort of housing, and the main clinical prognostic factors was examined. The influence of comfort of housing on prognosis was studied with the Cox model, while controlling for these factors. Interactions between type of housing and other prognostic factors also were tested. Results . Compared with patients living in a comfortable house, patients in the medium or no‐comfort categories were more likely to receive diagnosis at an advanced stage ( P = 0.03) and be treated by palliative therapy ( P = 0.0005). After adjustment for these factors and age, sex, place of residence, and tumor site, patients living in no comfort had a twofold higher risk of dying during the follow‐up period compared with patients living in comfortable housing, with the relative risk being 1.5 for the medium comfort category (95% confidence intervals, 1.3–3.2 and 1.2–1.7, respectively). This effect was more remarkable in patients with early‐stage tumors than in patients with advanced tumors. Conclusions . Such findings should prompt public health measures for earlier access to care structures for people in a lower social class and research for a better understanding of the host‐tumor relationship.