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Acquired immune deficiency syndrome‐related pulmonary non‐Hodgkin lymphoma regressing after zidovudine therapy
Author(s) -
Baselga Jose,
Krown Susan E.,
Telzak Edward E.,
Filippa Daniel A.,
Straus David J.
Publication year - 1993
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19930401)71:7<2332::aid-cncr2820710726>3.0.co;2-p
Subject(s) - zidovudine , medicine , lymphoma , immune system , hodgkin lymphoma , immunology , chemotherapy , oncology , human immunodeficiency virus (hiv) , viral disease
Background . Zidovudine is a thymidine analogue that has been reported to have antiviral and antineoplastic activity in vitro. Methods . The case of a patient with acquired immune deficiency syndrome (AIDS) and a pulmonary non‐Hodgkin lymphoma treated with zidovudine and no other treatment is presented. Results . The patient achieved a prolonged partial remission of a pulmonary non‐Hodgkin lymphoma while receiving zidovudine alone. Conclusions . Zidovudine may have antitumor effects in AIDS‐related lymphomas and should be evaluated for its antitumor potential.