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Adjuvant therapy in prostatic cancer
Author(s) -
Smith PH,
Parmar MKB
Publication year - 1993
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19930201)71:3+<992::aid-cncr2820711416>3.0.co;2-n
Subject(s) - medicine , prostatectomy , cancer , malignancy , adjuvant therapy , life expectancy , randomized controlled trial , clinical trial , adjuvant , surgery , prostate cancer , oncology , population , environmental health
Background . Prostatic cancer is an unusual malignancy because, commonly, it is slowly progressive and occurs at an age where the patient's life expectancy is short as a result of considerable competing mortality rates from other diseases. In addition, the place of radical surgery, i.e., radical prostatectomy is still not defined completely or established uniformly. Methods . This article attempts to offer comparisons of the initial forms of primary therapy and to determine the way in which adjuvant therapy may be tested and its results assessed. Results and Conclusion . Additional information should come from large‐scale randomized clinical trials involving several hundred patients in each treatment arm.