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DNA flow cytometry of epithelioid sarcoma
Author(s) -
PastelLevy Cecile,
Bell Debra A.,
Rosenberg Andrew E.,
Prefer Frederic,
Colvin Robert B.,
Flotte Thomas J.
Publication year - 1992
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19921215)70:12<2823::aid-cncr2820701216>3.0.co;2-9
Subject(s) - aneuploidy , epithelioid sarcoma , pathology , epithelioid cell , medicine , ploidy , sarcoma , flow cytometry , biology , immunohistochemistry , immunology , chromosome , genetics , gene
DNA ploidy of paraffin‐embedded tissue from 11 patients with epithelioid sarcoma and 20 control specimens (granuloma annulare and sarcoid) was studied. DNA aneuploidy was found in 64% of the epithelioid sarcomas and in none of the control samples. Aneuploidy did not correlate with necrosis, vascular invasion, or mitotic rate. There was also no association of aneuploidy with adverse outcome.