Premium
Orbital granulocytic sarcomas (myeloid sarcomas) in acute nonlymphocytic leukemia
Author(s) -
Shome Durjoy K.,
Gupta Naresh K.,
Prajapati Nirmal C.,
Raju G. M. Krishnam,
Choudhury Panna,
Dubey Anand P.
Publication year - 1992
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19921101)70:9<2298::aid-cncr2820700914>3.0.co;2-i
Subject(s) - medicine , leukemia , myeloid , sarcoma , myeloid leukemia , myeloid leukaemia , pathology , cancer research , oncology
In a series of 89 patients with acute leukemia, orbital granulocytic sarcomas were observed in 7. All these patients had acute nonlymphocytic leukemia, and they were all children. The orbital involvement usually was bilateral, and the patients had proptosis, conjunctival hemorrhage, and chemosis. Morphologic, cytochemical, and immunophenotypic analyses did not show a predilection for any particular myeloid cell type. Two patients had biphenotypic leukemias with myeloid components. The ocular manifestations responded well to chemotherapy irrespective of the hematologic response. Cancer 1992; 70:2298‐2301.