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Protocol for the prevention and treatment of oral sequelae resulting from head and neck radiation therapy
Author(s) -
Jansma Johan,
Vissink Arjan,
Spijkervet Fred K. L.,
Roodenburg Jan L. N.,
Panders Arend K.,
Vermey Albert,
Szabó Ben G.,
Johannes'sGravenmade E.
Publication year - 1992
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19921015)70:8<2171::aid-cncr2820700827>3.0.co;2-s
Subject(s) - medicine , osteoradionecrosis , mucositis , trismus , head and neck cancer , radiation therapy , regimen , quality of life (healthcare) , protocol (science) , sequela , surgery , pathology , nursing , alternative medicine
In addition to the desired antitumor effects, head and neck radiation therapy induces damage in normal tissues that may result in oral sequelae such as mucositis, hypo‐salivation, radiation caries, taste loss, trismus, soft‐tissue necrosis, and osteoradionecrosis. These sequelae may be dose‐limiting and have a tremendous effect on the patient's quality of life, Current policies to prevent these sequelae primarily are based on clinical experience and show great diversity. A protocol for the prevention and treatment of oral sequelae resulting from head and neck radiation therapy, based on fundamental research and data derived from the literature, is presented. The protocol is particularly applicable in centers with a dental team. This team should be involved at the time of initial diagnosis so that a successful preventive regimen is an integral part of the overall cancer treatment regimen.