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Radiosurgery for palliation of base of skull recurrences from head and neck cancers
Author(s) -
Kaplan Irving D.,
Adler John R.,
Hicks Wesley L.,
Fee Willard E.,
Goffinet Don R.
Publication year - 1992
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19921001)70:7<1980::aid-cncr2820700728>3.0.co;2-l
Subject(s) - medicine , radiosurgery , skull , asymptomatic , head and neck cancer , radiation therapy , radiography , head and neck , radiology , surgery , nuclear medicine
Background . Seven patients received stereotaxic radiosurgery for 10 lesions at the base of the skull (BOS) from recurrent head and neck malignant neoplasms. Methods . A radiation dose of 17.5–35.0 Gy was delivered as a single fraction. Follow‐up ranged from 1 to 14 months. Results . Nine lesions were symptomatic, and the symptoms improved in five and stabilized in four lesions. In addition, a significant radiographic response was observed in 4 of 10 recurrences. Cranial nerve signs developed in two patients, and an area of asymptomatic necrosis developed in one patient in the temporal lobe tip. Conclusions . From their brief experience, the authors conclude that stereotaxic radiosurgery may be a promising treatment in locally controlling recurrent head and neck cancers that involve the BOS. Cancer 1992; 70:1980–1984.