Premium
Intrapulmonary sublesions detected before surgery in patients with lung cancer
Author(s) -
Kunitoh Hideo,
Eguchi Kenji,
Yamada Kouzou,
Tsuchiya Ryousuke,
Kaneko Masahiro,
Moriyama Noriyuki,
Noguchi Masayuki
Publication year - 1992
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19921001)70:7<1876::aid-cncr2820700712>3.0.co;2-q
Subject(s) - medicine , lung cancer , lung , general surgery , surgery , oncology
Background . The treatment of patients with multiple intrapulmonary lesions remains controversial. Methods . Fifty‐three patients with lung cancer, in whom preoperative evaluation disclosed intrapulmonary nodules distinct from the main tumor, were analyzed retrospectively to establish the optimal treatment in such cases. Results . These sublesions proved to be intrapulmonary metastases (PM) in 16 cases (30%), multiple primary lung cancers in 7 cases (13%), and various nonmalignant lesions in the others. The survival of the 53 patients, and of patients with clinical Stage I/II disease in particular, compared favorably with that of all patients with resected lung cancer. Those with multiple sublesions had a poorer prognosis, irrespective of their nature. Although patients with PM as sublesions often had clinically advanced cancer, metastatic foci, per se, did not influence the survival data as calculated by a multivariate analysis. Conclusions . The authors conclude that the existence of a solitary intrapulmonary sublesion should not preclude surgical treatment, unless surgery is contraindicated because of other clinical and radiologic findings. Cancer 1992; 70:1876–1879.