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Testicular relapse in adult acute myelogenous leukemia
Author(s) -
Shafer Don W.,
Burris Howard A.,
O'Rourke Timothy J.
Publication year - 1992
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19920915)70:6<1541::aid-cncr2820700616>3.0.co;2-6
Subject(s) - medicine , bone marrow , leukemia , oncology
Testicular relapse (TR) in adult acute myelogenous leukemia (AML) is uncommon, occurring in only 1–2% of patients with bone marrow relapse. TR in the absence of systemic relapse has been reported previously in 2 adults and 12 children, of which 67% were monocytic variants of AML. This article presents the case of a 29‐year‐old man with AML that relapsed in his testicle without evidence of bone marrow relapse. This patient and the two previously mentioned adults experienced bone marrow relapse within 2 months and died within 7 months of their TR. TR in adult myelogenous leukemia should be considered a harbinger of systemic relapse and suggests a need for aggressive local and systemic therapy.