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Nutrition and colorectal cancer
Author(s) -
Levin Bernard
Publication year - 1992
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19920915)70:4+<1723::aid-cncr2820701612>3.0.co;2-3
Subject(s) - colorectal cancer , medicine , obesity , bromodeoxyuridine , dietary fiber , pathogenesis , cancer , cancer research , physiology , food science , biology , immunohistochemistry
Environmental and genetic factors play an important role in the cause and pathogenesis of colorectal cancer. In addition to nutritional aspects, other environmental factors include physical exercise, energy intake, obesity, and parity. Dietary components currently under study are dietary fiber, fat, fruits, vegetables, and calcium. Intermediate markers of colonic proliferation, including bromodeoxyuridine and proliferating cell nuclear antigen incorporation, are being used to evaluate the response of the colonic epithelium to putative chemopre‐ventative agents.