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Necrotizing pneumonitis caused by 5‐fluorouracil infusion. A complication of a hickman catheter
Author(s) -
Manheimer Forrest,
Aranda Conrado P.,
Smith Robert L.
Publication year - 1992
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19920715)70:2<554::aid-cncr2820700228>3.0.co;2-3
Subject(s) - medicine , catheter , surgery , pneumonitis , complication , lung , thrombosis
The authors report the case of a patient with a Hickman catheter that migrated into the lung parenchyma. The resultant inadvertent infusion of 5‐fluorouracil caused necrotizing chemical pneumonitis. Possible mechanisms of catheter migration include the lateral orientation of the catheter tip and the partial thrombosis of the innominate vein and superior vena cava. The patient recovered but had residual contraction fibrosis of the right upper lobe of the lung. Cancer 1992; 70:554‐556.