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Significance of aneuploidy in melanoma of the extremity
Author(s) -
Van Oven M. W.,
Oosferhuis J. W.,
DamMeiring A.,
Baas P. C.,
Schraffordf Koops H.
Publication year - 1992
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19920701)70:1<109::aid-cncr2820700118>3.0.co;2-j
Subject(s) - aneuploidy , medicine , melanoma , flow cytometry , ploidy , pathology , nuclear dna , cancer research , biology , immunology , chromosome , genetics , mitochondrial dna , gene
Tumor nuclear DNA content was determined by flow cytometry in routinely prepared paraffin blocks from 25 primary malignant melanomas of the extremities. Twelve of the tumors were aneuploid, and 13 were euploid. In this series the presence of aneuploidy appeared to have no prognostic value.