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Recurrent adult nephroblastoma long‐term remission after surgery plus adjuvant high‐dose chemotherapy, radiation therapy, and allogeneic bone marrow transplantation
Author(s) -
Hupperets Pierre S.,
Havenith Miek G.,
Blijham Geert H.
Publication year - 1992
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19920615)69:12<2990::aid-cncr2820691221>3.0.co;2-6
Subject(s) - medicine , etoposide , surgery , chemotherapy , cyclophosphamide , radiation therapy , nephrectomy , bone marrow , oncology , kidney
The authors report a case of Stage IV, unfavorable histo‐logic type adult nephroblastoma. The patient was treated with multimodal therapy: combination chemotherapy consisting of cyclophosphamide, doxorubicin, cisplatin, and etoposide succeeded by nephrectomy and radiation therapy. After a disease‐free period of 27 months, a para‐rectal relapse was treated by surgery, high‐dose chemotherapy, and allogeneic bone marrow transplantation (BMT). The patient is alive and disease‐free 3.5 years after BMT.