Premium
Prognostic importance of human papillomavirus type 16 DNA in cervical cancer
Author(s) -
Girardi F.,
Fuchs P.,
Haas J.
Publication year - 1992
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19920515)69:10<2502::aid-cncr2820691019>3.0.co;2-7
Subject(s) - medicine , cervical cancer , parametrial , oncology , human papillomavirus , koilocyte , cancer , pathology , cervical carcinoma , cervical intraepithelial neoplasia
Human papillomavirus (HPV) type 16 DNA is frequent in invasive cervical cancers. Among 43 patients with invasive cervical cancer, HPV‐16‐positive tumors spread to the parametrial and pelvic lymph nodes significantly more often than did HPV‐16‐negative tumors ( P < 0.05). Demonstration of HPV‐16 DNA in invasive cervical cancers may be an additional prognostic factor for this disease.