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The fibroma‐like variant of epithelioid sarcoma
Author(s) -
Mirra Joseph M.,
Kessler Stephen,
Bhuta Sunita,
Eckardt Jeffrey
Publication year - 1992
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19920315)69:6<1382::aid-cncr2820690614>3.0.co;2-y
Subject(s) - dermatofibroma , epithelioid sarcoma , vimentin , pathology , epithelioid cell , medicine , sarcoma , fibroma , keratin , lesion , anatomy , immunohistochemistry
Five cases of a previously undescribed variant of epithelioid sarcoma are presented. This variant differs from the usual lesion in its absence of the typical necrobiotic nodular epithelioid pattern. It is instead composed of deceptively bland fibrohistiocytic and myoid cells arranged in a fibroma‐like or dermatofibroma‐like pattern with an affinity for osseous involvement. The clinical presentation, ultrastructural features, and presence of vimentin and low molecular weight keratin within the tumor cells justifies their designation as an epithelioid sarcoma variant. Cancer 1992; 69:1382‐1395.