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The polymerase chain reaction and cancer diagnostics
Author(s) -
Lyons John
Publication year - 1992
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19920315)69:6+<1527::aid-cncr2820691304>3.0.co;2-n
Subject(s) - polymerase chain reaction , medicine , cancer , polymerase , computational biology , cancer research , gene , genetics , biology
In this review, I describe the polymerase chain reaction (PCR) and its application to cancer diagnostics. I present recent improvements to PCR methodology, and describe some state‐of‐the‐art detection methods and approaches used to diagnose various cancer markers, including ras genes, BCR/ abl translocations, and G‐proteins. Cancer 1992; 69:1527‐1531.