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Treatment of primary squamous cell carcinoma of the upper urinary tract
Author(s) -
Nativ Ofer,
Reiman Herbert M.,
Lieber Michael M.,
Zincke Horst
Publication year - 1991
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19911215)68:12<2575::aid-cncr2820681208>3.0.co;2-v
Subject(s) - medicine , upper urinary tract , urinary system , basal cell , carcinoma , urology , presentation (obstetrics) , survival rate , oncology , surgery
Forty‐six patients with primary squamous cell carcinoma of the upper urinary tract treated over a 44‐year period were studied. The lack of characteristic presentation caused delay in diagnosis. Associated urinary calculi were found in only five (11%) of the patients. Almost all of the tumors were histologically high grade; at surgery, 84% of the tumors were locally advanced or metastatic. Prognosis is poor independent of treatment; the overall 24‐month survival rate was 22%. Comparison with a previous study of renal pelvic transitional cell carcinoma indicates that these two forms of urothelial neoplasm are biologically different. Cancer 68:25750–2578, 1991.