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Malignant transformation of aneurysmal bone cyst, with an analysis of the literature
Author(s) -
Kyriakos Michael,
Hardy David
Publication year - 1991
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19911015)68:8<1770::aid-cncr2820680821>3.0.co;2-7
Subject(s) - aneurysmal bone cyst , medicine , curettage , expansive , osteosarcoma , malignant transformation , lesion , cyst , surgery , tibia , radiology , pathology , compressive strength , materials science , composite material
An 11‐year‐old girl had a lytic, benign‐appearing, expansive lesion of the distal tibia radiologically interpreted as an aneurysmal bone cyst (ABC). Tissue from two extensive curettage procedures was also histologically diagnosed as ABC. Approximately 50 months after the onset of symptoms, and 28 months after her last curettage, a highly pleomorphic osteosarcoma developed. The patient had not received prior radiation therapy. The cases in the literature of possible malignant transformation of ABC are reviewed. The authors separate their case from telangiectatic osteosarcoma, and from “ aneurysmal bone cyst‐like osteosarcoma”.