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Primary pulmonary adenocarcinoma with enteric differentiation
Author(s) -
Tsao MingSound,
Fraser Richard S.
Publication year - 1991
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19911015)68:8<1754::aid-cncr2820680818>3.0.co;2-e
Subject(s) - medicine , adenocarcinoma , neuroendocrine differentiation , pathology , gastrointestinal tract , neoplasm , lung , epithelium , paneth cell , columnar cell , cancer , small intestine , prostate cancer
A pulmonary neoplasm with cytologic characteristics typical of differentiated small intestinal epithelium is reported. Individual cells showed features suggesting columnar absorptive, goblet, Paneth, and neuroendocrine cell differentiation. Thorough investigation and follow‐up for 4 years did not identify a primary tumor other than in the lung. The occurrence of such a neoplasm at this site is evidence for the existence of a common stem cell in the lower respiratory and gastrointestinal tract mucosa.