Premium
Cisplatin‐based chemotherapy in a renal transplant recipient
Author(s) -
Lindley Celeste M.,
Gordon Teressa R.,
Tremont Stephen J.
Publication year - 1991
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19910901)68:5<1113::aid-cncr2820680537>3.0.co;2-2
Subject(s) - medicine , cisplatin , chemotherapy , testicular cancer , regimen , renal transplant , nephrotoxicity , seminoma , chemotherapy regimen , intensive care medicine , oncology , surgery , kidney
Cisplatin‐based chemotherapy is the treatment of choice for metastatic testicular cancer; however, the safety of conventional regimens in renal transplant recipients has been questioned. The authors report the course of a renal transplant recipient successfully treated with a cisplatin‐based chemotherapy regimen for testicular seminoma and review three additional cases that have been reported in the English language literature to date. Emphasis is placed on review of the safety, optimal administration, and appropriate monitoring of cisplatin and controversy regarding the need for continued administration of immunosuppressive therapy.